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[Acquired ventricular septal defect during infective endocarditis]

F Tarasoutchi1, M Grinberg, J A Barreto Filho

  • 1Instituto do Coração do Hospital das Clínicas-FMUSP, São Paulo.

Arquivos Brasileiros De Cardiologia
|September 1, 1994
PubMed
Summary

Acquired ventricular septal defect, a complication of infective endocarditis, presents with specific clinical signs. Early surgical intervention is crucial for patients with aortic valve endocarditis and these symptoms.

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Cardiac Surgery

Background:

  • Infective endocarditis (IE) can lead to serious cardiac complications.
  • Aortic valve disease and aortic ring abscesses are predisposing factors for IE complications.
  • Acquired ventricular septal defect (VSD) is a rare but severe complication of IE.

Observation:

  • Five male patients with acquired VSD secondary to infective endocarditis were studied.
  • All patients had pre-existing aortic valve disease and aortic ring abscess.
  • Clinical diagnosis was achieved in 4 cases, indicated by systolic murmur, left parasternal thrill, and right-heart failure.

Findings:

  • Congestive heart failure occurred in 60% of patients.
  • In-hospital mortality rate was 40%.

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  • No specific causative pathogen was identified.

    • Implications:

    • Acquired VSD should be suspected in patients with aortic valve IE presenting with new systolic murmurs, parasternal thrill, or right-heart failure.
    • Prompt surgical treatment is essential for managing acquired VSD in this context.
    • This highlights the critical need for timely diagnosis and intervention in complex IE cases.