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Updated: Aug 11, 2026

Induction of Graft-versus-host Disease and In Vivo T Cell Monitoring Using an MHC-matched Murine Model
Published on: August 29, 2012
Detection of minimal residual disease in autologous grafts
1Ahmanson Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
Abstract:
There is increasing evidence that the presence of tumor cells within autologous hematopoietic cell grafts may increase the risk of relapse of disease post-transplant. The sensitive detection of minimal residual disease is therefore central to improving the outcome of autologous transplantation, irrespective of the source of the graft. This review presents a comparative evaluation of the sensitivity and specificity of the currently available methods for tumor detection.
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