Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Critical issues in periodontal research

¹Department of Periodontics, School of Medicine, University of Washington, Seattle 98195, USA.

Journal of Dental Research

|April 1, 1995

Summary

Periodontitis research has advanced understanding of its causes and treatments. Key challenges remain in identifying susceptible individuals and essential microbial pathogens for effective periodontitis therapy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP.

The Journal of biological chemistry·2022

Same author

Self-reported measures for surveillance of periodontitis.

Journal of dental research·2013

Same author

Constructive medicine and industry.

Journal of the American Medical Association·2010

Same author

Study of absorption from crystalline insulin pellets and solutions at various sites in rabbits.

The Journal of laboratory and clinical medicine·2010

Same author

Serial tests of hippuric acid formation in hepatitis after intravenous sodium benzoate.

Gastroenterology·2010

Same author

Eosinophilia on a gastro-intestinal hospital service; case reports on four patients with a syndrome of eosinophila, leucocytosis and gastro-intestinal complaints.

Gastroenterology·2010

Area of Science:

Periodontology
Microbiology
Immunology

Background:

Periodontitis affects a small population, with prevalence potentially decreasing.
Susceptible individuals and risk indicators for severe disease are not well understood.
The role of numerous implicated microbial species in periodontitis etiology is unclear.

Purpose of the Study:

To review major achievements in periodontitis research.
To identify critical unresolved issues in periodontitis epidemiology, microbiology, pathogenesis, diagnosis, and therapy.
To highlight areas for future research and therapeutic development.

Main Methods:

Literature review of epidemiological, microbiological, and pathogenetic studies.
Analysis of current diagnostic and therapeutic approaches.
Identification of knowledge gaps and future research directions.

Main Results:

Significant progress has been made in understanding periodontitis pathogenesis and developing therapies.
Essential microbial pathogens and host susceptibility factors remain to be fully identified.
The complex interplay between microbial flora, host factors, and environmental influences requires further elucidation.

Conclusions:

While therapeutic strategies are emerging, a comprehensive understanding of periodontitis etiology and host-pathogen interactions is crucial.
Further research is needed to pinpoint specific microbial targets and host susceptibility factors for personalized periodontitis treatment.
Developing effective vaccines and targeted anti-inflammatory therapies holds promise for modifying disease progression.

Related Experiment Videos