Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Micturitional disturbance in myotonic dystrophy

R Sakakibara1, T Hattori, M Tojo

  • 1Department of Neurology, Kashima Rosai Hospital, Japan.

Journal of the Autonomic Nervous System
|March 18, 1995
PubMed
Summary

Micturitional disturbances, including urination difficulty and incontinence, affect a third of myotonic dystrophy patients. These symptoms may stem from lower urinary tract muscle changes or pelvic nerve dysfunction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Current status of cancer pain control in home hospice care--assessment by family members].

Gan to kagaku ryoho. Cancer & chemotherapy·1999
Same author

Effects of FK506 on experimental membranous glomerulonephritis induced by cationized bovine serum albumin in rats.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1998
Same author

Famotidine-induced acute interstitial nephritis.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1998
Same author

Henoch-Schönlein purpura nephritis associated with methicillin-resistant Staphylococcus aureus infection.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1998
Same author

Proliferative response of CD8+ gamma delta+ T cells to Streptococcus sanguis in patients with Behçet's disease.

Ocular immunology and inflammation·1998
Same author

Biomarker and morphological characteristics of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis.

Medical and pediatric oncology·1998

Area of Science:

  • Neurology
  • Urology

Background:

  • Micturitional disturbances are often overlooked in myotonic dystrophy patients.
  • Previous research has not extensively detailed urinary symptoms in this population.

Purpose of the Study:

  • To investigate the prevalence and characteristics of micturitional disturbances in patients with myotonic dystrophy.
  • To explore potential underlying causes of these urinary symptoms.

Main Methods:

  • Detailed micturitional histories were collected from six patients.
  • Urodynamic studies were conducted to assess bladder and urethral function.
  • Urethral sphincter electromyography and motor unit analysis were performed.

Main Results:

  • 33% of patients reported micturitional symptoms, including difficulty urinating, frequency, urgency, and stress incontinence.

Related Experiment Videos

  • Urodynamic findings included low urethral closure pressure, varied bladder capacities, detrusor hyperreflexia, and atonic cystometrograms.
  • Electromyography indicated abnormal reflexes and external sphincter muscle potentials.

    • Conclusions:

    • Micturitional disturbances are present in a significant portion of myotonic dystrophy patients.
    • Potential causes include dystrophic changes in lower urinary tract muscles and supranuclear pelvic nerve dysfunction.