Related Experiment Videos
Vitamin K-dependent coagulopathy in a British Devon rex cat
J D Littlewood1, S C Shaw, L M Coombes
1Animal Health Trust, Newmarket, Suffolk.
The Journal of Small Animal Practice
|March 1, 1995
Summary
A bleeding disorder in Devon rex cats, linked to vitamin K-dependent clotting factors, was identified. Oral vitamin K treatment successfully corrected the clotting times, resolving the hemorrhage.
Area of Science:
- Veterinary Medicine
- Hematology
- Canine and Feline Medicine
Background:
- Vitamin K is essential for synthesizing specific coagulation factors.
- Disorders affecting vitamin K metabolism can lead to hemostatic abnormalities.
- The Devon rex breed is being investigated for potential inherited conditions.
Observation:
- A Devon rex cat experienced significant bleeding post-castration.
- Initial treatment involved plasma transfusion to manage hemorrhage.
- Clotting times were monitored to assess hemostasis.
Findings:
- The cat was diagnosed with deficiencies in vitamin K-dependent coagulation factors.
- Oral administration of vitamin K effectively normalized clotting times.
- This confirmed a vitamin K-related bleeding disorder in the patient.
Implications:
- This case confirms a specific bleeding disorder in Devon rex cats in the UK.
- Early diagnosis and vitamin K supplementation can manage this condition.
- Further research into the genetic basis of this disorder in Devon rex cats is warranted.