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AIDS-related lymphoma: radiologic features in pediatric patients
G P Siskin1, J O Haller, S Miller
1Department of Radiology, State University of New York Health Science Center at Brooklyn 11203, USA.
Purpose:
To determine the clinical, pathologic, and radiologic features in pediatric patients with acquired immunodeficiency syndrome (AIDS)-related lymphoma and to compare these features with those in adult patients with AIDS-related lymphoma.
Materials And Methods:
Clinical and radiologic findings were retrospectively reviewed in nine children (aged 1-15 years) with AIDS-related lymphoma. All patients had neoplastic changes that were not consistent with hyperplastic lymphoid tissue. The children underwent ultrasonography, computed tomography, magnetic resonance imaging, and plain radiography.
Results:
Sites of involvement by malignant non-Hodgkin lymphoma at diagnosis were the liver (n = 7), spleen (n = 5), kidney (n = 4), central nervous system (n = 2), and testis and bone (n = 1). Symptoms included seizures, respiratory distress, testicular swelling, and increased abdominal girth.
Conclusion:
Children with AIDS-related lymphoma have symptoms distinct from those found in adults, but clinical, radiologic, and pathologic findings show that almost any anatomic site in these children can be involved.