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[Psoriasis: diagnosis and therapy]

R Panizzon1

  • 1Dermatologische Klinik und Poliklinik, Universitätsspital Zürich.

Praxis
|May 30, 1995
PubMed
Summary
This summary is machine-generated.

Psoriasis treatment involves managing epidermal proliferation and inflammation. Therapies range from local treatments like salicylic acid and UV light to systemic options, with calcipotriol offering a non-irritating alternative.

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Area of Science:

  • Dermatology
  • Immunology

Context:

  • Psoriasis pathogenesis involves epidermal proliferation and inflammation.
  • Cytokine production and adhesion molecule expression are key factors.
  • Accurate diagnosis relies on case history, clinical findings, and sometimes biopsy.

Purpose:

  • To outline the diagnostic and therapeutic approaches for psoriasis.
  • To discuss various treatment modalities, both local and internal.
  • To highlight advancements in psoriasis treatment.

Summary:

  • Psoriasis diagnosis requires clinical assessment and potentially biopsy for characteristic histopathology.
  • Local treatments include baths, salicylic acid, tar, dithranol, and corticosteroids.
  • Calcipotriol, a vitamin D derivative, offers effective treatment without discoloration or atrophy, comparable to corticosteroids and combinable with UV therapy.

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Impact:

  • Provides a comprehensive overview of psoriasis management strategies.
  • Emphasizes the efficacy and benefits of newer treatments like calcipotriol.
  • Informs clinicians and patients about available therapeutic options and their characteristics.