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[Lung transplantation]

M Tamm1, C Bolliger, M Solèr

  • 1Departement of Innere Medizin, Universitätsklinik Basel.

Schweizerische Medizinische Wochenschrift
|June 3, 1995
PubMed
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Lung transplantation offers a life-saving option for end-stage lung disease patients, improving survival and quality of life. Careful patient selection and surgical management are key to successful outcomes and minimizing complications.

Area of Science:

  • Cardiovascular and Respiratory System Sciences
  • Surgical Sciences
  • Transplantation Medicine

Background:

  • Lung transplantation is a viable treatment for end-stage lung disease, offering improved survival for patients with conditions like emphysema and cystic fibrosis.
  • Patients often experience severely diminished quality of life, with dyspnea, hypoxia, and reduced physical capacity, necessitating advanced interventions.

Purpose of the Study:

  • To review the indications, techniques, and outcomes of lung transplantation.
  • To highlight the importance of donor-recipient selection, surgical expertise, and postoperative care for successful lung transplantation.

Main Methods:

  • Review of current practices in lung transplantation, including single lung transplantation (SLT) and bilateral lung transplantation (BLT).
  • Discussion of patient selection criteria, contraindications, and common complications.

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  • Analysis of factors influencing patient survival and quality of life post-transplantation.

    • Main Results:

    • Bilateral lung transplantation (BLT) has largely replaced double lung transplantation, offering advantages in avoiding cardiopulmonary bypass and reducing airway anastomosis issues.
    • Key indications include emphysema, cystic fibrosis, fibrosing alveolitis, and primary pulmonary hypertension (PPH).
    • Early complications such as organ failure, bleeding, and acute rejection are common but treatable with prompt diagnosis and intervention.

    Conclusions:

    • Lung transplantation is a critical option for end-stage lung disease, with BLT becoming the preferred technique.
    • Successful outcomes depend on meticulous donor-recipient matching, experienced surgical teams, and vigilant postoperative management.
    • Early detection and management of complications are essential for optimizing patient survival and recovery.