Toward reducing risks and costs of egg donation: a preliminary report
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1Faulkner Centre for Reproductive Medicine, Boston, Massachusetts 02130, USA.
Objective:
To use clomiphene citrate for ovarian stimulation of egg donors as a means of reducing the risk, discomfort, and inconvenience for egg donors and reducing costs for recipients.
Design:
Prospective nonrandomized clinical study.
Setting:
Private reproductive center.
Patients:
Egg donation recipients and their anonymous donors.
Intervention:
Clomiphene citrate was administered to egg donors rather than a GnRH agonist and gonadotropins before oocyte retrieval.
Main Outcome Measure:
Pregnancy.
Results:
Eleven oocyte retrievals were performed and conception occurred in four cycles, three of which delivered.
Conclusion:
Clomiphene citrate appears to be a reasonable less expensive method of ovarian stimulation for egg donation in normospermic males and appears more acceptable to potential donors.