Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Central auditory processing in Alzheimer's disease

A L Strouse1, J W Hall, M C Burger

  • 1Division of Hearing and Speech Sciences, School of Medicine, Vanderbilt University, Nashville, Tennessee, USA.

Ear and Hearing
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early results of starting a fracture liaison service for fragility hip fractures in a regional South African hospital.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025
Same author

Orthopaedic-related pathological conditions in the paediatric population presenting at outreach clinics in central South Africa over a 20-year period.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025
Same author

CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma.

British journal of cancer·2025
Same author

Strangulated Hernia.

Iowa medical journal·2023
Same author

AAV-mediated gene transfer of a checkpoint inhibitor in combination with HER2-targeted CAR-NK cells as experimental therapy for glioblastoma.

Oncoimmunology·2022
Same author

Ports' criticality in international trade and global supply-chains.

Nature communications·2022
Same journal

Community-Informed Adaptation of a School-Based Hearing Health Intervention: Formative Evaluation for an Effectiveness-Implementation Trial.

Ear and hearing·2026
Same journal

Hearing Difficulty, Health Literacy, and Poorer Health Among Adults in the United States: 2016 Behavioral Risk Factor Surveillance Study.

Ear and hearing·2026
Same journal

Cultural Differences in Listening Environments Between Hispanic and White Non-Hispanic Cochlear Implant Users.

Ear and hearing·2026
Same journal

Detection of Inner Ear Malformations Based on Simple Anatomical Measurements: A Model Approach.

Ear and hearing·2026
Same journal

Avoiding Cisplatin-Related Hearing Loss, Including Implementing Sodium Thiosulfate as Otoprotectant Into Daily Pediatric Clinical Practice: Proceedings Based on Evidence and Expert Opinion From the Ototoxicity Taskforce of the SIOP Supportive Care Network.

Ear and hearing·2026
Same journal

Quantifying Miscommunications in Triadic Conversations: Effects of Hearing Impairment, Hearing Aids, and Background Noise.

Ear and hearing·2026
See all related articles

Individuals with early to moderate Alzheimer's disease (AD) exhibit impaired central auditory processing compared to healthy older adults. This suggests a need for auditory screening in AD patients.

Area of Science:

  • Neuroscience
  • Audiology
  • Gerontology

Background:

  • Alzheimer's disease (AD) is a progressive neurodegenerative disorder.
  • Central auditory processing (CAP) refers to the brain's interpretation of auditory information.
  • The impact of early to middle-stage AD on CAP is not fully understood.

Purpose of the Study:

  • To investigate whether individuals with early to middle-stage Alzheimer's disease (AD) demonstrate impaired central auditory processing.
  • To compare the central auditory function of AD patients with that of non-demented elderly individuals.

Main Methods:

  • A comprehensive auditory test battery, including peripheral and central assessments, was administered to 10 mild-to-moderate AD patients and 10 matched controls.
  • Peripheral tests included immittance audiometry, pure-tone and speech audiometry, and otoacoustic emissions.

Related Experiment Videos

  • Central auditory tests comprised synthetic sentence identification, dichotic digits, dichotic sentence identification, pitch patterns, and duration patterns.

    • Main Results:

    • Peripheral auditory status was comparable between groups, with no significant differences in high-frequency hearing or speech recognition.
    • A significant difference was observed in low-frequency hearing sensitivity in the left ear, with AD subjects showing poorer thresholds.
    • The AD group performed significantly worse than controls on four out of five central auditory processing measures.

    Conclusions:

    • The observed central auditory processing deficits in AD patients are unlikely to be solely artifacts of cognitive decline.
    • Findings support the screening for central auditory dysfunction in the Alzheimer's disease population.
    • Addressing auditory processing impairments may improve psychiatric assessments and audiological management in AD.