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[HELLP syndrome. 7-year experience at the National Institute of Perinatology]
M Argueta Zúñiga1, C Neri Méndez, J Lira Plascencia
1Instituto Nacional de Perinatología, México, D.F.
Insights
This study on HELLP syndrome found Type I cases led to more severe maternal and newborn complications, higher hospital stays, and increased mortality. Understanding these features is crucial for better outcomes.
Area of Science:
- Obstetrics and Gynecology
- Perinatology
- Maternal-Fetal Medicine
Background:
- HELLP syndrome is a severe pregnancy complication.
- It is associated with significant maternal and perinatal risks.
- Understanding its epidemiology and clinical features is vital for timely intervention.
Purpose of the Study:
- To describe the epidemiology and clinical features of HELLP syndrome.
- To establish diagnostic criteria and classification.
- To determine maternal and perinatal morbidity and mortality.
Main Methods:
- Retrospective study of 36 patients with HELLP syndrome and their newborns.
- Data collected over seven years at the National Institute of Perinatology.
- Analysis of clinical features, diagnostic types, pregnancy history, and outcomes.
Main Results:
- 44.6% were Type I and 55.6% were Type II HELLP syndrome.
- Preterm pregnancies (28-36 weeks) and severe preeclampsia/eclampsia were common.
- Type I cases showed higher complication rates, longer hospital stays, 5.55% maternal mortality, and 32.43% perinatal mortality.
Conclusions:
- HELLP syndrome, particularly Type I, is associated with severe maternal and perinatal complications.
- Outcomes for newborns are often unsatisfactory, with high rates of asphyxia and mortality.
- Improved prenatal care and timely management are essential for reducing morbidity and mortality.
Abstract:
We studied 36 patients with Hellp syndrome and her newborn during seven years in the National Institute of Perinatology (INPer). The objective of this study is show the epidemiology and clinic features, unite diagnostic criteria and classification, furthermore establish morbidity and mortality maternal and perinatal. The 44.6% (16/36) was type I, and 55.6% (20) was type II. The average of pregnancies was 3. The 38.9% (14/36) received regular prenatal control. Both types were more common in patients with preterm pregnancies, between 28-36 weeks. The patients with severe preeclampsia and eclampsia were more common. The cases with type I had more complications and stayed on hospital more time. The maternal mortality was 5.55%. Perinatal outcomes were unsatisfactory, with high incidence of asphyxiated newborn. The newborn of patients with type I had more severe complications and stayed more time on the hospital. The perinatal mortality was 32.43%.