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Related Experiment Videos

Diffuse pulmonary lymphangiomatosis: CT findings

S J Swensen1, T E Hartman, J R Mayo

  • 1Department of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905, USA.

Journal of Computer Assisted Tomography
|May 1, 1995
PubMed
Summary

Computed tomography (CT) reveals distinctive findings in diffuse pulmonary lymphangiomatosis (DPL). Key features include thickened septa and mediastinal fat infiltration, aiding diagnosis but requiring biopsy for confirmation.

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Area of Science:

  • Radiology
  • Pulmonary Medicine
  • Pathology

Background:

  • Diffuse pulmonary lymphangiomatosis (DPL) is a rare condition affecting the lungs.
  • Accurate diagnosis relies on identifying characteristic imaging features.

Observation:

  • Retrospective review of CT scans from eight pathologically proven DPL patients (ages 3-35).
  • Analysis focused on infiltrative patterns, pleural abnormalities, and lymphadenopathy.

Findings:

  • Consistent CT findings include smooth thickening of interlobular septa and bronchovascular bundles.
  • Ground-glass attenuation, mediastinal fat infiltration, and perihilar infiltration were observed in most patients.
  • Pleural effusions, thickening, and calcifications were present in a subset of patients.

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Implications:

  • The described CT features are highly suggestive of DPL.
  • While CT findings are distinctive, lung biopsy remains essential for definitive diagnosis.
  • Early identification via CT can guide further diagnostic and management strategies.