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Related Experiment Videos

Chronic cough associated with subacute bacterial endocarditis

L Martin1, C Gustaferro

  • 1Division of Pulmonary and Critical Care Medicine, Mt. Sinai Medical Center, Cleveland, OH 44106-4198, USA.

Mayo Clinic Proceedings
|July 1, 1995
PubMed
Summary

Subacute bacterial endocarditis, a rare cause of chronic cough, was identified in a patient despite extensive workups. Treatment with antibiotics resolved the persistent cough, highlighting endocarditis as an uncommon but treatable condition.

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Area of Science:

  • Infectious Diseases
  • Cardiology
  • Pulmonology

Background:

  • Chronic cough is a common symptom with numerous potential causes.
  • Subacute bacterial endocarditis (SBE) is infrequently associated with cough in medical literature.
  • Reviews on chronic cough rarely include infective endocarditis as a differential diagnosis.

Observation:

  • A 74-year-old male presented with a 7-month history of nonproductive chronic cough.
  • Extensive diagnostic workup, including imaging and bronchoscopy, failed to identify the cause.
  • Persistently elevated erythrocyte sedimentation rate and weight loss prompted further investigation.

Findings:

  • Blood cultures revealed Streptococcus constellatus bacteremia.
  • Transesophageal echocardiogram identified mitral valve vegetation, confirming infective endocarditis.

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  • Antibiotic therapy led to complete resolution of the patient's chronic cough.

    • Implications:

    • Bacteremia and endocarditis should be considered in the differential diagnosis of unexplained chronic cough.
    • This case underscores the importance of considering less common etiologies for persistent respiratory symptoms.
    • Prompt diagnosis and treatment of infective endocarditis can effectively resolve associated symptoms like chronic cough.