Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Azithromycin and clarithromycin

D Schlossberg1

  • 1Medical College of Pennsylvania, Philadelphia, USA.

The Medical Clinics of North America
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Azithromycin and clarithromycin offer convenient, well-tolerated alternatives to traditional macrolides for common infections. Their improved dosing and broader spectrum provide therapeutic advantages and new options for various conditions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect on compression of lowering the design adiabat in the SQ-n campaign.

Physical review. E·2025
Same author

Inferring fusion nuclear burnwidths with low gain photomultiplier impulse response functions.

The Review of scientific instruments·2024
Same author

Neutron imaging of the deuterium-tritium tamping gas volume in an inertial confinement fusion hohlraum.

The Review of scientific instruments·2024
Same author

Learning from each other: Cross-cutting diagnostic development activities between magnetic and inertial confinement fusion (invited).

The Review of scientific instruments·2024
Same author

Energy Principles of Scientific Breakeven in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

Diagnosing the origin and impact of low-mode asymmetries in ignition experiments at the National Ignition Facility.

Physical review. E·2023
Same journal

Care Transitions Continue to Evolve.

The Medical clinics of North America·2026
Same journal

Navigating the Gaps: A Comprehensive Overview of Care Transitions Across the Continuum.

The Medical clinics of North America·2026
Same journal

Care Transitions and Value-Based Payment Models in the United States.

The Medical clinics of North America·2026
Same journal

Technology and Innovation in Care Transitions: Imagining the Future of Postdischarge Care.

The Medical clinics of North America·2026
Same journal

Primary Care, Specialists, and Hospitals: Bridging the Gaps in Communication and Coordination.

The Medical clinics of North America·2026
Same journal

Social Determinants of Health: Unique Considerations in Transitions of Care.

The Medical clinics of North America·2026
See all related articles

Area of Science:

  • Infectious Diseases
  • Pharmacology
  • Dermatology

Background:

  • Azithromycin and clarithromycin serve as alternatives to conventional macrolides.
  • They are used for dermatologic, upper respiratory, and lower respiratory tract infections.
  • These antibiotics offer improved tolerability, reduced toxicity, and convenient dosing schedules.

Purpose of the Study:

  • To evaluate azithromycin and clarithromycin as alternative macrolide therapies.
  • To highlight the therapeutic advantages of their dosing convenience and broader spectrum.
  • To explore their potential in treating additional opportunistic infections.

Main Methods:

  • Comparative analysis of macrolide therapies.
  • Review of clinical data on patient compliance and therapeutic outcomes.

Related Experiment Videos

  • Exploration of expanded antimicrobial spectrum.

    • Main Results:

    • Azithromycin and clarithromycin demonstrate better tolerability and less toxicity than conventional macrolides.
    • Once-daily dosing significantly improves patient compliance (95%) compared to multiple daily doses (58%).
    • These agents offer expanded therapeutic options for infections caused by H. influenzae, MAC in AIDS, MOTT, and leprosy.

    Conclusions:

    • Azithromycin and clarithromycin are effective and advantageous alternatives for routine infections.
    • Their convenient dosing and broader spectrum enhance therapeutic efficacy and patient compliance.
    • Further research may expand their application to opportunistic infections like toxoplasmosis and cryptosporidiosis.