[Description of two cases of transient hyperphosphatasemia in infancy and childhood]

The authors describe two cases of benign transient hyperphosphatesamia of infancy. This form is not so frequent in childhood and the following criteria must be present for a correct diagnosis: 1) Patient age of less than 5 years. 2) Variable symptoms. 3) No bone or liver disease noted on physical examination. 4) No other biochemical or laboratory evidence for bone or liver disease. 5) A return to normal serum alkaline phosphatase levels within 4 months with no sequelae. We want underline the uselessness of vitamin D therapy and the importance of a deepened study about biochemical and laboratory parameters in all patients affected by alkaline hyperphosphatesamia, to exclude a possible severe disease.