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Celiac sprue in an asymptomatic elderly man

N R Cordum1, B M McGuire, D Nelson

  • 1University of Kansas Medical Center, Kansas City, USA.

Minnesota Medicine
|May 1, 1995
PubMed
Summary

Celiac sprue can present without typical symptoms like diarrhea. Unexplained iron deficiency in patients warrants investigation for this condition, even if other classic signs are absent.

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Area of Science:

  • Gastroenterology
  • Hematology
  • Internal Medicine

Background:

  • Celiac sprue is an autoimmune disorder triggered by gluten ingestion.
  • Classic symptoms include diarrhea and steatorrhea, but presentations vary.
  • Hematologic abnormalities can be early indicators.

Observation:

  • An asymptomatic patient exhibited hematologic abnormalities during routine screening.
  • Initial treatments for vitamin B-12, folate, and iron deficiencies were partially effective.
  • Diagnosis of celiac sprue was established despite the lack of overt gastrointestinal symptoms.

Findings:

  • Celiac sprue can manifest solely through hematologic abnormalities.
  • Suboptimal response to standard deficiency treatments may indicate an underlying malabsorptive condition.
  • Asymptomatic celiac sprue is a recognized clinical presentation.

Implications:

  • Clinicians should consider celiac sprue in cases of unexplained iron deficiency.
  • Screening for celiac sprue may be beneficial in patients with persistent unexplained anemia.
  • Early diagnosis of celiac sprue, even in asymptomatic individuals, is crucial for effective management and preventing complications.

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