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Mortality in anorexia nervosa

¹University Department of Psychological Medicine, Christchurch School of Medicine, New Zealand.

The American Journal of Psychiatry

|July 1, 1995

Summary

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Anorexia nervosa is associated with a significant mortality rate, estimated at 5.6% per decade. This eating disorder poses a greater risk than general psychiatric conditions or the general population.

Area of Science:

Psychiatry
Public Health
Epidemiology

Background:

Anorexia nervosa is a severe eating disorder with significant health consequences.
The long-term mortality associated with anorexia nervosa requires ongoing investigation.

Purpose of the Study:

To determine the mortality rate over time for individuals with anorexia nervosa.
To synthesize existing data on anorexia nervosa mortality through meta-analysis.

Main Methods:

A meta-analytic approach was employed.
Weighted linear regression was used to combine mortality data from 42 studies.

Main Results:

The pooled crude mortality rate from all causes of death was 5.9% (178 deaths/3,006 subjects).

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The estimated aggregate mortality rate was 0.56% annually, equating to approximately 5.6% per decade.

Conclusions:

The mortality rate for anorexia nervosa is considerably higher than for female psychiatric inpatients.
Individuals with anorexia nervosa face a substantially elevated mortality risk compared to the general population.