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Related Experiment Videos

Vancomycin-resistant Enterococcus faecium sepsis following persistent colonization

G A Noskin1, I Cooper, L R Peterson

  • 1Department of Medicine, Northwestern University Medical School, Chicago, Ill., USA.

Archives of Internal Medicine
|July 10, 1995
PubMed
Summary
This summary is machine-generated.

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Vancomycin-resistant enterococci (VRE) can colonize patients indefinitely. Asymptomatic VRE carriage can lead to life-threatening sepsis, especially in immunocompromised individuals.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Oncology

Background:

  • Vancomycin-resistant enterococci (VRE) are significant nosocomial pathogens.
  • Patients with compromised immune systems are at high risk for VRE infections.

Observation:

  • A patient with leukemia experienced prolonged colonization with vancomycin-resistant Enterococcus faecium (VREfm).
  • This colonization persisted despite unknown interventions.

Findings:

  • The patient ultimately succumbed to sepsis caused by the multidrug-resistant VREfm.
  • This case highlights that VRE colonization can be indefinite.

Implications:

  • Asymptomatic VRE carriage poses a substantial risk for invasive infections.

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  • VRE poses a serious threat in healthcare settings, particularly for vulnerable patient populations.