Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current concepts in neuro-oncology

L J Rubinstein

    Advances in Neurology
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Neuro-oncology research is advancing with new agents and tools for studying brain tumors. This chapter explores cancer theories, immunology, and epigenetics in neural neoplasms.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Contiguous Sarcomatous and Gliomatous Tissue in Intracranial Tumours [Abstract].

    Proceedings of the Royal Society of Medicine·2009
    Same author

    Murine immune response to Neisseria meningitidis group C capsular polysaccharide: analysis of monoclonal antibodies generated in response to a thymus-independent antigen and a thymus-dependent toxoid conjugate vaccine.

    Infection and immunity·1999
    Same author

    Murine immune responses to Neisseria meningitidis group C capsular polysaccharide and a thymus-dependent toxoid conjugate vaccine.

    Infection and immunity·1998
    Same author

    The growth of two murine hemangioendotheliomas intracranially, subcutaneously, and in culture, and their comparison with human cerebellar hemangioblastomas: morphological and immunohistochemical studies.

    Acta neuropathologica·1992
    Same author

    A simple method for coating native polysaccharides onto nitrocellulose.

    Journal of immunological methods·1991
    Same author

    Neuron-associated class III beta-tubulin isotype, microtubule-associated protein 2, and synaptophysin in human retinoblastomas in situ. Further immunohistochemical observations on the Flexner-Wintersteiner rosettes.

    Laboratory investigation; a journal of technical methods and pathology·1991

    Area of Science:

    • Neuroscience
    • Oncology
    • Molecular Biology

    Background:

    • Neuro-oncology is experiencing a resurgence driven by new neuro-oncogenic agents and experimental tools.
    • Research focuses on brain tumor study using radiotherapy, chemotherapy, and immunology.
    • Current interest areas include cancer theories, immunology, and epigenetics in neural neoplasms.

    Purpose of the Study:

    • To discuss naturally occurring and experimentally induced nervous system tumors.
    • To relate these tumors to key areas of oncology: somatic mutation, viral theories, immunological surveillance, and epigenetic mechanisms.
    • To highlight the suitability of neural neoplasms for studying epigenetic phenomena.

    Main Methods:

    • Review of observations on naturally occurring and experimentally induced nervous system tumors.

    Related Experiment Videos

  • Discussion of established and emerging theories in cancer research (somatic mutation, viral, immunological, epigenetic).
  • Utilizing new tools for experimental brain tumor study (radiotherapeutic, chemotherapeutic, immunological).
  • Main Results:

    • Neural neoplasms are ideal models for studying epigenetic phenomena due to distinct markers.
    • Allows clear definition of divergent differentiation stages in neurocytogenesis.
    • Provides insights into altered gene expression patterns in neoplastic systems.

    Conclusions:

    • Advances in neuro-oncology are facilitated by new agents and experimental methodologies.
    • Understanding epigenetic mechanisms in neural neoplasms is crucial for cancer research.
    • Neural neoplasms offer unique advantages for dissecting complex biological processes in cancer development.