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Adverse effects of topical corticosteroid use
1Department of Medicine, University of California, School of Medicine, San Francisco, USA.
The Western Journal of Medicine
|February 1, 1995
Summary
Topical corticosteroids are effective for skin conditions but can cause serious side effects. Prescribers must be aware of potential risks, including hypothalamic-pituitary-adrenal axis suppression and cataracts.
Area of Science:
- Dermatology
- Endocrinology
- Ophthalmology
Background:
- Topical corticosteroids are widely used for various skin conditions.
- Their efficacy, availability, and low cost can lead to underestimation of risks.
Purpose of the Study:
- To highlight the potential adverse effects of topical corticosteroid use.
- To emphasize the importance of prescriber awareness regarding these side effects.
Main Methods:
- Review of known adverse effects associated with topical corticosteroid therapy.
Main Results:
- Adverse effects range from systemic issues like hypothalamic-pituitary-adrenal axis suppression, Cushing's disease, osteonecrosis, and cataracts.
- Cutaneous side effects include tinea and contact dermatitis.
Conclusions:
- Despite benefits, topical corticosteroids carry significant risks.
- Physicians must maintain vigilance regarding side effects, similar to parenteral medications.