Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retrograde cerebral perfusion: overview, techniques and results

S A Raskin1, J S Coselli

  • 1Baylor College of Medicine, Department of Surgery, Houston, TX 77030, USA.

Perfusion
|January 1, 1995
PubMed
Summary

Retrograde cerebral perfusion during hypothermic circulatory arrest enables successful aortic arch aneurysm repair. This technique significantly decreases neurological complications, improving patient outcomes after complex cardiovascular surgery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aortic arch repair today: open repair is best for most arch lesions.

The Journal of cardiovascular surgery·2015
Same author

Quality assessment in open surgical repair of thoracic aortic disease.

Deutsche medizinische Wochenschrift (1946)·2009
Same author

Analysis of multigenerational families with thoracic aortic aneurysms and dissections due to TGFBR1 or TGFBR2 mutations.

Journal of medical genetics·2009
Same author

Smallpox: elimination or possible re-infection?

Maryland medicine : MM : a publication of MEDCHI, the Maryland State Medical Society·2002
Same author

S100beta correlates with neurologic complications after aortic operation using circulatory arrest.

The Annals of thoracic surgery·2001
Same author

A new predictive model for adverse outcomes after elective thoracoabdominal aortic aneurysm repair.

The Annals of thoracic surgery·2001

Area of Science:

  • Cardiovascular Surgery
  • Vascular Surgery
  • Thoracic Surgery

Background:

  • Aortic arch aneurysm repair historically involved high morbidity and mortality.
  • Advancements by Crawford and Coselli have improved procedure viability.
  • Increased patient numbers now undergo successful aortic arch repair.

Purpose of the Study:

  • To review techniques and results of aortic arch repair.
  • To evaluate retrograde cerebral perfusion during circulatory arrest with profound hypothermia.
  • To assess the reduction of neurological morbidity in transverse aortic arch replacement.

Main Methods:

  • Utilized retrograde cerebral perfusion (RCP) with profound hypothermia and circulatory arrest.
  • Surgically treated 88 patients between February 1992 and October 1993.

Related Experiment Videos

  • Focused on repairs not achievable under standard conditions.

    • Main Results:

    • Profound hypothermia and circulatory arrest were key to successful clinical outcomes.
    • Retrograde cerebral perfusion facilitated complex aortic arch repairs.
    • The technique allowed patients to resume normal lives post-operation.

    Conclusions:

    • Retrograde cerebral perfusion is a vital advancement in aortic arch aneurysm repair.
    • Profound hypothermia and circulatory arrest are critical determinants of success.
    • This approach significantly lessens neurological morbidity following surgical repair.