Ceftazidime as monotherapy for fever and neutropenia: experience in a community hospital
G A Bizette1, B J Brooks, S Alvarez
1Dept of Internal Medicine, Ochsner Clinic, New Orleans, La 70121.
Abstract:
Fever and neutropenia is occurring in a wider variety of clinical settings, and the proper antibiotic therapy for its treatment is an area of debate. Our study is a retrospective analysis of the experience of the Oncology Division of the Medical Center of Baton Rouge, which used ceftazidime as monotherapy in the empiric treatment of fever and neutropenia. A total of 53 episodes in 38 patients were studied. Using ceftazidime as monotherapy in our study population was associated with an 8% mortality rate, indicating that monotherapy is a viable option for the treatment of fever and neutropenia.
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