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PET versus SPECT in distinguishing radiation necrosis from tumor recurrence in the brain
C A Buchpiguel1, J B Alavi, A Alavi
1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Abstract:
Two cases of postsurgical brain tumor evaluation in which MRI was inconclusive are discussed. Functional imaging techniques, such as FDG-PET and 201TI SPECT, were used in both cases for distinguishing radiation necrosis from tumor recurrence. These methods proved to be complimentary. For Patient 1, FDG-PET showed more limitations compared to 201TI SPECT. FDG-PET results on the other hand, were consistent with the final diagnosis and the SPECT image was false positive for tumor recurrence in Patient 2.