Related Experiment Video
Updated: Aug 18, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
Characteristics associated with pathogenicity of avian septicaemic Escherichia coli strains
F Fantinatti1, W D Silveira, A F Castro
1Departamento de Microbiologia e Imunologia, IB Universidade Estadual de Campinas, São Paulo, Brazil.
Abstract:
Seventeen strains of E. coli, isolated from chickens with colisepticaemia, were studied with respect to their pathogenic characteristics including: serum resistance, toxin production, pathogenicity for one-day-old chicks, colicin production, adherence to and invasiveness of HeLa cells, plasmid DNA profile and SDS-PAGE electrophoresis of membrane proteins, as well as electron microscope studies and hemagglutination tests for fimbriae. We concluded that the adherence to and the invasiveness of HeLa cells were not related to the pathogenicity of these strains for chickens. Plasmid profiles were not related to the bactericidal activity of the serum. Toxin production was correlated to the highest levels of pathogenicity. Some of the strains had mannose-resistant fimbriae. SDS-PAGE of membrane proteins of all the strains which were either not pathogenic or which had a very high LD50 lacked two major protein subunits of 40.7 kDa and 28.8 kDa found only in pathogenic strains.
More Related Videos
Related Concept Videos
Reservoir of Infection
Colonisation of Pathogens
Determinants of Bacterial Pathogenicity and Virulence
Regulation of Bacterial Virulence
Bacterial Gastroenteritis
Cholera

