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[Hepatic candidiasis caused by Candida glabrata]
E Pinès1, D Malbec, M P Lepennec
1Service de Médecine interne, Centre hospitalier intercommunal Robert-Ballanger, Aulnay-Sous-Bois.
Annales De Gastroenterologie Et D'Hepatologie
|October 1, 1994
Summary
Disseminated candidiasis, often involving the liver, is rising. This case highlights diagnosing liver metastases from Candida glabrata using CT scans and abscess analysis, leading to successful treatment.
Area of Science:
- Mycology
- Infectious Diseases
- Hepatology
Background:
- Disseminated candidiasis incidence is increasing globally.
- Liver involvement is common in disseminated candidiasis but often underdiagnosed.
- Candida glabrata is an emerging cause of invasive fungal infections.
Observation:
- A case of disseminated candidiasis caused by Candida glabrata with liver metastases is presented.
- Hepatic lesions were identified using computed tomography (CT) scans.
- Parasitological examination of liver abscess aspirates confirmed the fungal presence.
Findings:
- Successful treatment of Candida glabrata liver metastases was achieved with amphotericin-B and flucytosine.
- A cumulative dose of 1g amphotericin-B was administered.
- CT-guided puncture-aspiration was crucial for diagnosis.
Implications:
- This case underscores the importance of considering and diagnosing hepatic involvement in disseminated candidiasis.
- Candida glabrata should be recognized as a significant pathogen in invasive candidiasis, particularly with liver involvement.
- Effective therapeutic strategies involving amphotericin-B and flucytosine can lead to favorable outcomes.