Related Experiment Videos
Genomic organization and DNA sequence of the human catecholamine-sulfating phenol sulfotransferase gene (STM)
T P Dooley1, P Probst, P B Munroe
1Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78228.
Biochemical and Biophysical Research Communications
|December 15, 1994
Abstract:
The human monoamine neurotransmitter-preferring phenol sulfotransferase (M-PST) plays an essential role in the sulfation of catecholamines, such as dopamine. The cDNA encoding M-PST has been reported, and we have recently identified cosmid clones from human chromosome 16p11.2 for this gene, STM. Plasmid subclones derived from the STM cosmid clones were subjected to dideoxynucleotide chain termination sequencing to determine the genomic organization and DNA sequence of STM. The gene encoding full-length STM is approximately 6.4 kb and contains 8 exons and 7 introns.