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Infantile meningioma
M C Molleston1, C J Moran, K A Roth
1Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Mo.
Abstract:
Childhood meningiomas are unusual, and meningiomas in patients less than 1 year of age are exceedingly rare. We report a case of a meningioma with malignant histologic features in a 6-month-old child who has had an excellent postoperative course. The pathologic features in relation to prognosis, as well as the magnetic resonance imaging characteristics of the case are presented. The literature is reviewed and implications for therapeutic management are discussed.
Insights
Malignant meningioma is rare in infants, but a 6-month-old patient had an excellent outcome after surgery. This case highlights the importance of understanding rare pediatric brain tumors for effective treatment.
Area of Science:
- Pediatric neuro-oncology
- Neurosurgery
- Pathology of central nervous system tumors
Background:
- Meningiomas are tumors arising from the meninges, the membranes surrounding the brain and spinal cord.
- Meningiomas are rare in children, and exceptionally rare in infants under one year of age.
Observation:
- A 6-month-old infant presented with a meningioma exhibiting malignant histologic features.
- The patient underwent surgical resection and experienced an excellent postoperative course.
Findings:
- The study details the pathological features of the infant's meningioma and its relation to prognosis.
- Magnetic resonance imaging (MRI) characteristics of this rare pediatric meningioma are presented.
Implications:
- Review of existing literature on pediatric meningiomas.
- Discussion of therapeutic management strategies for rare infant meningiomas.