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METREE: a program package for inferring and testing minimum-evolution trees

A Rzhetsky1, M Nei

  • 1Institute of Molecular Evolutionary Genetics, Pennsylvania State University, University Park 16802.

Computer Applications in the Biosciences : CABIOS
|July 1, 1994
PubMed
Summary
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The METREE program estimates phylogenetic trees using the minimum evolution method. This user-friendly software runs on personal computers and includes tree visualization tools.

Area of Science:

  • Computational Biology
  • Bioinformatics
  • Evolutionary Biology

Background:

  • Phylogenetic tree estimation is crucial for understanding evolutionary relationships.
  • The minimum evolution method offers an efficient approach to inferring evolutionary history.
  • Software tools are needed to facilitate the application of phylogenetic methods.

Purpose of the Study:

  • To introduce the METREE program package for phylogenetic tree estimation.
  • To provide a user-friendly and accessible tool for applying the minimum evolution method.
  • To enable visualization and printing of inferred phylogenetic trees.

Main Methods:

  • The METREE program package utilizes the minimum evolution method for phylogenetic tree construction.
  • The software is implemented in Turbo C 2.0 for compatibility with IBM-compatible personal computers.

Related Experiment Videos

  • A mathematical coprocessor is recommended for optimal performance.

    • Main Results:

    • The METREE package provides a straightforward, menu-driven interface for users.
    • It successfully estimates phylogenetic trees based on the minimum evolution principle.
    • An integrated program allows for the visualization and printing of the resulting phylogenetic trees.

    Conclusions:

    • METREE offers a practical and accessible solution for phylogenetic tree estimation using the minimum evolution method.
    • The program's design prioritizes ease of use and compatibility with standard personal computers.
    • The inclusion of visualization and printing functionalities enhances its utility for researchers.