Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interictal language fluency in temporal lobe epilepsy

R A Howell1, M M Saling, D C Bradley

  • 1Department of Psychology, Monash University.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
|September 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bilateral volume reduction in posterior hippocampus in psychosis of epilepsy.

Journal of neurology, neurosurgery, and psychiatry·2019
Same author

Do the Elderly Get the Message? A Comparative Study of Stories Produced Verbally and as a Text Message.

Journal of psycholinguistic research·2016
Same author

A novel mutation af Cln3 associated with delayed-classic juvenile ceroid lipofuscinois and autophagic vacuolar myopathy.

European journal of medical genetics·2015
Same author

Factors affecting subjective memory complaints in the AIBL aging study: biomarkers, memory, affect, and age.

International psychogeriatrics·2013
Same author

Expression of the transmembrane lysosomal protein SCARB2/Limp-2 in renin secretory granules controls renin release.

Nephron. Experimental nephrology·2013
Same author

Multiple Symmetrical Lipomatosis--a mitochondrial disorder of brown fat.

Mitochondrion·2013
Same journal

The cognitive construction of moral scenes: Associations of visuospatial ability and impulsivity with perspective and vividness in mental simulation.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Theta band activity during event-file retrieval is influenced by stimulus salience in the preceding action episode.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Language recovery in Hungarian speakers with aphasia: Roles of phonology and intraindividual variability.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Neural and behavioral dissociations of self-focused and other-focused incentives in trust.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

A multiverse analysis of the logical memory test and plasma biomarkers of Alzheimer's disease.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Reading and writing impairments in Spanish-speaking individuals with primary progressive aphasia: A single-case series study.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
See all related articles

Patients with left temporal lobe epilepsy (LTLE) may experience speech fluency disruptions, particularly under high cognitive load. These challenges are linked to lexical retrieval, not solely LTLE.

Area of Science:

  • Neuroscience
  • Epilepsy Research
  • Speech and Language Pathology

Background:

  • Left temporal lobe epilepsy (LTLE) is associated with language production deficits, notably in confrontation naming.
  • These subtle difficulties are not always apparent in spontaneous conversational speech.
  • Experimental comparison of speech fluency in LTLE and right temporal lobe epilepsy (RTLE) is needed.

Purpose of the Study:

  • To experimentally compare speech fluency between patients with LTLE and RTLE.
  • To investigate speech fluency using pause-to-speech ratios.
  • To explore the relationship between fluency variations and cognitive demands.

Main Methods:

  • Studied pause-to-speech ratios in patients with unilateral temporal lobe epilepsy (LTLE, RTLE) and primary generalized epilepsy (PGE) as controls.

Related Experiment Videos

  • Elicited speech samples by having subjects describe New Yorker cartoons.
  • Measured pauses (200-4000 ms) and divided by total phonation time.

    • Main Results:

    • The global pause-to-speech ratio did not significantly differentiate between LTLE, RTLE, and PGE groups.
    • The LTLE group exhibited a trend towards longer pause durations.
    • Increased pause duration variability in LTLE during initial trials suggested vulnerability to planning demands.

    Conclusions:

    • Speech fluency measures, like pause-to-speech ratio, may not fully capture subtle language production difficulties in LTLE.
    • Individual differences in fluency appear related to high-level lexical retrieval capacities, not specific to LTLE.
    • Cognitive load and planning demands can impact speech fluency in individuals with temporal lobe epilepsy.