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Updated: Aug 16, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
[Polypous endocarditis of the tricuspid valve. The morphological changes in the heart and lung in one case]
Abstract:
A case of polypous endocarditis which affects the tricuspid valve and whose genesis remains unclear (a septic state, an idiopathic disease?) is described. Clinically the disease has taken its course as a chronically recurring form of pulmonary thromboembolism. Morphologically it concerns to a massive fibroplastic verrucous endocarditis of the tricuspid valve and a more slightly expressed similar process in the wall of the right atrium and ventricle, combined with a significant fibrosis of the myocardium. The death has come from a massive thrombotic embolism in the two branches of the pulmonary artery on the background of a great number of small thromboembolic and hemorrhagenic infarctions with a different duration in the two lobes of the lung, which lead to an adaptable reconstruction of many lung vessels. The presence of a discrete affection of the aortic valve according to a rheumatic type and the combination of the disease, in the described case, with essential hypertension and thrombophlebitis undergone in the past, give a reason to discuss the possibility of taking into account these diseases in etiopathogenesis of the described myocardiopathy.
Insights
This case study details polypous endocarditis affecting the tricuspid valve, presenting as recurrent pulmonary thromboembolism. The findings highlight complex cardiac and pulmonary pathology, emphasizing the need to consider associated conditions in its development.
Area of Science:
- Cardiology
- Pathology
Background:
- Polypous endocarditis is a rare condition affecting heart valves.
- The etiology of polypous endocarditis, particularly when affecting the tricuspid valve, often remains unclear, with potential links to septic states or idiopathic origins.
Observation:
- A case of polypous endocarditis involving the tricuspid valve is presented.
- Clinically, the condition manifested as chronic, recurrent pulmonary thromboembolism.
- Morphological examination revealed massive fibroplastic verrucous endocarditis of the tricuspid valve, with associated right atrial and ventricular involvement, and significant myocardial fibrosis.
Findings:
- The patient's death resulted from massive thrombotic embolism in the pulmonary artery branches.
- Extensive thromboembolic and hemorrhagic pulmonary infarctions with adaptive vascular reconstruction were observed.
- A discrete rheumatic-type aortic valve affection was noted.
Implications:
- The co-occurrence of essential hypertension and a history of thrombophlebitis suggests these may play a role in the etiopathogenesis of the observed myocardiopathy.
- This case underscores the complex interplay of factors contributing to severe endocarditis and its sequelae.
- Further research into the etiopathogenesis of idiopathic polypous endocarditis is warranted.
Related Concept Videos
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Endocarditis II: Clinical Features of Infective Endocarditis
Rheumatic Heart Disease I: Introduction
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

