Cellular and soluble CD4 measurements in cynomolgus monkeys

Anti-human CD4 monoclonal antibodies have been successfully used to label T-lymphocytes in Cynomolgus monkeys by two different methods. A magnetisable bead separation was used prior to immunogold labelling of lymphocytes in one of the methods. In addition, an assay for soluble CD4 has been applied to the sera of these monkeys.