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Adverse drug effects

G T Terézhalmy1, M A Pyle

  • 1Department of Dentistry, Cleveland Clinic Foundation, Ohio.

Dental Clinics of North America
|October 1, 1994
PubMed
Summary
This summary is machine-generated.

All drugs carry risks of adverse side effects and interactions. The potential for harm means no biologically active agent can be considered completely safe.

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Area of Science:

  • Pharmacology
  • Clinical Toxicology

Background:

  • Drugs often produce beneficial effects alongside adverse side effects.
  • Assessing the precise frequency of clinically significant adverse drug events remains challenging.

Purpose of the Study:

  • To highlight the inherent risks associated with all biologically active agents.
  • To underscore the importance of considering drug interactions and drug-induced illnesses.

Main Methods:

  • Literature review and synthesis of existing pharmacological principles.
  • Analysis of the concept of drug safety in clinical practice.

Main Results:

  • Clinically important adverse effects are common, though difficult to quantify.
  • The potential for drug-drug and drug-disease interactions is substantial.

Conclusions:

  • No biologically active agent is entirely safe due to the potential for adverse effects and interactions.
  • A comprehensive understanding of drug risks is crucial for patient safety.