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Chromosomal localization of four human VH1-like protein-tyrosine phosphatases
K J Martell1, S Kwak, D J Hakes
1Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor 48109.
Genomics
|July 15, 1994
Abstract:
Four human protein-tyrosine phosphatase (PTPase) genes of the VH1-like subclass were cloned by low-stringency screening of a genomic library. These genes were localized to their respective chromosomes by G-banding and fluorescence in situ hybridization. The genes were localized to unique regions of different chromosomes: CL100, a stress-induced PTPase, to 5q35; PAC-1, a mitogen-induced nuclear PTPase, to 2q11;hVH-3 to 10q25; and hVH-4 to 10q11.