DNA adducts of the mitomycins

Reductive activation of mitomycin A by thiols.

Organic letters·2001

Solution structure of a guanine-N7-linked complex of the mitomycin C metabolite 2,7-diaminomitosene and DNA. Basis of sequence selectivity.

Biochemistry·2001

Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.

Journal of medicinal chemistry·2001

Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol.

Biochemical pharmacology·2001

Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells.

Chemical research in toxicology·2000

Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity.

Bioorganic & medicinal chemistry·2000

Practical approaches to control mycotoxins.

IARC scientific publications·2013

Economics of mycotoxins: evaluating costs to society and cost-effectiveness of interventions.

IARC scientific publications·2013

Risk assessment and risk management of mycotoxins.

IARC scientific publications·2013

Mycotoxins and human health.

IARC scientific publications·2013

Effects in food-producing animals.

IARC scientific publications·2013

Analysis of mycotoxins.

IARC scientific publications·2013

RETRACTED: Aburjania et al. Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells. Molecules 2020, 25, 4940.

Molecules (Basel, Switzerland)·2026

SiaRNA: a siamese neural network with bidirectional cross-attention for pairwise siRNA-mRNA efficacy prediction.

Frontiers in bioinformatics·2026

Beyond Antioxidant Activity: Redox-Inflammatory Network Modulation as a Framework for the Multi-Organ Pharmacology of Moringa oleifera.

Journal of experimental pharmacology·2026

[Retracted] 2',4'-dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC-3 human prostate cancer cell growth by induction of apoptosis.

Oncology letters·2026

Novel Compounds as 5‑HT2A Agonists for Treating Mental Illness or CNS Disorders.

ACS medicinal chemistry letters·2026

Safety and Efficacy of Atogepant for Migraine Prevention: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Cureus·2026

Related Experiment Videos

DNA adducts of the mitomycins

Related Concept Videos

Reductive activation of mitomycin A by thiols.

Solution structure of a guanine-N7-linked complex of the mitomycin C metabolite 2,7-diaminomitosene and DNA. Basis of sequence selectivity.

Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.

Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol.

Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells.

Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity.

Practical approaches to control mycotoxins.

Economics of mycotoxins: evaluating costs to society and cost-effectiveness of interventions.

Risk assessment and risk management of mycotoxins.

Mycotoxins and human health.

Effects in food-producing animals.

Analysis of mycotoxins.

RETRACTED: Aburjania et al. Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells. Molecules 2020, 25, 4940.

SiaRNA: a siamese neural network with bidirectional cross-attention for pairwise siRNA-mRNA efficacy prediction.

Beyond Antioxidant Activity: Redox-Inflammatory Network Modulation as a Framework for the Multi-Organ Pharmacology of Moringa oleifera.

[Retracted] 2',4'-dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC-3 human prostate cancer cell growth by induction of apoptosis.

Novel Compounds as 5‑HT2A Agonists for Treating Mental Illness or CNS Disorders.

Safety and Efficacy of Atogepant for Migraine Prevention: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Related Experiment Videos

DNA adducts of the mitomycins

Related Concept Videos

Related Articles