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Coadministration of fluvoxamine increases serum concentrations of haloperidol
D G Daniel1, C Randolph, G Jaskiw
1Clinical Brain Disorders Branch, NIMH Neuroscience Center at Saint Elizabeths, Washington, D.C.
Journal of Clinical Psychopharmacology
|October 1, 1994
Abstract:
Four patients with chronic schizophrenia were treated with a combination of fluvoxamine, haloperidol, and benztropine. The combination significantly impaired performance on tests of delayed recall memory and attentional function. Haloperidol concentrations in serum were monitored in three patients and were robustly elevated by fluvoxamine.