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Identification of an activator of the retinoid X receptor
C Pathirana1, R A Heyman, S B Lazarchik
1Ligand Pharmaceuticals Inc., San Diego, California 92121.
Journal of Natural Products
|October 1, 1994
Abstract:
A metabolite of all-trans retinoic acid produced by insect cells was discovered to activate the intracellular retinoic acid X receptor. The compound, beta-glucopyranosyl 9-cis-retinoate [1], was purified and its structure was determined by analysis of spectroscopic data.