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Pathways of cysteine metabolism in MND/ALS
A Pean1, G B Steventon, R H Waring
1School of Biochemistry, University of Birmingham, Edgbaston, UK.
Journal of the Neurological Sciences
|July 1, 1994
Abstract:
Analysis of plasma from MND/ALS patients has shown no significant differences in metabolism of cysteine derivatives, although a sub-set of the population has raised glutamate values. Cysteine dioxygenase was found to have reduced activity in vitro, consistent with previous findings of a high plasma cysteine/sulphate ratio.