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Related Experiment Videos

Shock, sepsis, and the gut

B F Rush1

  • 1UMDNJ-New Jersey Medical School, Newark 07103.

New Jersey Medicine : the Journal of the Medical Society of New Jersey
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

Bacteria move from the gut to the bloodstream after hemorrhagic shock. Research is ongoing to determine the role of this bacterial translocation in sepsis development.

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Area of Science:

  • Microbiology
  • Sepsis Pathophysiology
  • Trauma Research

Background:

  • Bacterial translocation from the gut to systemic circulation is a known consequence of hemorrhagic shock in humans.
  • The clinical significance of this translocation in the development of sepsis remains under investigation.

Purpose of the Study:

  • To review current research on the role of gut bacterial translocation in sepsis following hemorrhagic shock.
  • To synthesize findings from UMDNJ-New Jersey Medical School research in this area.

Main Methods:

  • Literature review of existing studies.
  • Analysis of research conducted at UMDNJ-New Jersey Medical School.

Main Results:

  • Established phenomenon of bacterial translocation post-hemorrhagic shock.

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  • Ongoing evaluation of the link between bacterial translocation and sepsis.

    • Conclusions:

    • Bacterial translocation is a confirmed event after hemorrhagic shock.
    • Further research is required to fully elucidate its contribution to sepsis pathogenesis.