Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Eosinophilia caused by parasites

S D Mawhorter1

  • 1Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20894.

Pediatric Annals
|August 1, 1994
PubMed
Summary

Eosinophilia, an elevated eosinophil count, is not a reliable sole diagnostic tool for parasitic infections due to its association with various disorders and spontaneous resolution. Accurate diagnosis requires considering parasite life cycles and may necessitate repeated testing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Parasitic infections in solid organ transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2013
Same author

Histoplasmosis in solid organ transplant recipients: 10 years of experience at a large transplant center in an endemic area.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2009
Same author

Clinical characteristics of 13 solid organ transplant recipients with ganciclovir-resistant cytomegalovirus infection.

Transplant infectious disease : an official journal of the Transplantation Society·2003
Same author

The humoral immune response to influenza vaccination in lung transplant patients.

The European respiratory journal·2002
Same author

Who should receive hepatitis A vaccine?

Cleveland Clinic journal of medicine·2001
Same author

Protease-sparing regimen in a real-life practice with naïve patients: an equal opportunity approach?

HIV clinical trials·2001

Area of Science:

  • Clinical Medicine
  • Parasitology
  • Immunology

Background:

  • Eosinophilia, defined as an absolute eosinophil count exceeding 500 cells/mm³, is a hematological finding.
  • Its association with numerous disorders complicates its utility as a standalone diagnostic marker.

Purpose of the Study:

  • To evaluate the diagnostic limitations of eosinophilia in screening for parasitic infections, particularly in expatriates.
  • To highlight the importance of considering parasite life cycles in the diagnostic workup of eosinophilia.

Main Methods:

  • Review of existing literature on eosinophilia and parasitic infections.
  • Analysis of the etiological associations of eosinophilia.
  • Consideration of diagnostic strategies for helminthic infections.

Main Results:

  • Eosinophilia is linked to a wide array of conditions, reducing its specificity for parasitic infections.
  • Only tissue-invasive helminths reliably induce eosinophilia, limiting its application for other parasite types.
  • Eosinophilia can resolve spontaneously, necessitating longitudinal evaluation and consideration of parasite life cycles.

Conclusions:

  • Eosinophilia alone is insufficient for diagnosing parasitic infections.
  • Accurate diagnosis requires integrating clinical context, parasite life cycle knowledge, and potentially repeated stool examinations or serology.
  • Referral to travel medicine specialists is advised for complex cases involving helminthic parasites.

Related Experiment Videos