[Change in right ventricular diastolic function in children and adolescents with mucoviscidosis--a Doppler...

The present study investigated the right ventricular filling pattern with Dopplerechocardiography in childhood and adolescent patients (n = 31) with cystic fibrosis and in normal subjects. The results show that, as the pulmonary pressure increases (RPEP/AT > or = 1.0), the peak flow velocity during atrial contraction and the triangle under the atrial velocity are significantly increased while the acceleration half-time is significantly decreased. These are sensitive parameters for right ventricular diastolic dysfunction.