Intestinal lipid metabolism in suckling rats infected with Giardia duodenalis

We carried out a quantitative and qualitative analysis of intestinal digestion of neutral lipids in suckling rats infected with Giardia duodenalis. Total lipids were measured after extraction from the contents of the stomach, proximal and distal small bowel, caecum and colon. Amounts gradually fell from the stomach to the colon and were identical in infected animals and controls, although high values were occasionally found in the caecum of infected rats. Relative glyceride quantities were determined by means of high-performance thin-layer chromatography. Triglycerides were absent from the distal small bowel, and only free fatty acids and cholesterol were present in the caecum, reflecting normal digestion of neutral lipids in infected suckling rats. Our results suggest that G. duodenalis does not impair intestinal fat digestion in suckling rats.