Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Tumor marker analyses--valuable tools if used correctly]

O P Børmer1, E Paus, K Nustad

  • 1Sentrallaboratoriet, Det Norske Radiumhospital, Oslo.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|November 20, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased cerebrospinal fluid levels of nerve cell biomarkers in narcolepsy with cataplexy.

Sleep medicine·2014
Same author

Candidate epitopes for measurement of hCG and related molecules: the second ISOBM TD-7 workshop.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine·2013
Same author

Activation of EphA receptors on CD4+CD45RO+ memory cells stimulates migration.

Journal of leukocyte biology·2010
Same author

Characterization of monoclonal antibodies directed against squamous cell carcinoma antigens: report of the second TD-10 workshop.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine·2009
Same author

The usefulness of detecting thyroglobulin in fine-needle aspirates from patients with neck lesions using a sensitive thyroglobulin assay.

Diagnostic cytopathology·2007
Same author

Alpha fetoprotein is increasing with age in ataxia-telangiectasia.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2007

Current tumor marker tests lack cancer specificity, often showing elevated levels in non-malignant conditions. These markers are valuable for cancer staging and monitoring, not for screening healthy individuals.

Area of Science:

  • Oncology
  • Biochemistry
  • Clinical Diagnostics

Context:

  • Tumor marker assays are widely used in clinical practice.
  • Current assays often lack cancer specificity.
  • Markers are typically normal products of epithelial tissues.

Purpose:

  • To evaluate the utility and limitations of current tumor marker assays.
  • To clarify the role of tumor markers in cancer diagnosis and management.
  • To emphasize the importance of clinical judgment in interpreting tumor marker results.

Summary:

  • Tumor markers are not cancer-specific and can be elevated in non-malignant diseases due to their origin as normal tissue products.
  • Their primary applications include cancer staging, assessing surgical completeness, relapse detection, and monitoring treatment response.

Related Experiment Videos

  • Normal tumor marker values do not rule out cancer, and screening healthy populations is not recommended.

    • Impact:

    • Highlights the limitations of tumor markers for cancer screening.
    • Reinforces the critical role of clinical context in interpreting tumor marker data.
    • Guides appropriate utilization of tumor markers in oncology patient management.