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Deficient repair of UV-induced DNA damage in immature human T cells

M Hartwig1

  • 1Max Delbrück Center for Molecular Medicine, Berlin.

Zeitschrift Fur Gerontologie
|September 1, 1994
PubMed

As compared with quiescent lymphocytes, human thymocytes were found in the nucleoid sedimentation assay to be deficient in UV-induced DNA repair. Therefore, the age-related repair deficiency of human lymphocytes can result from the increased proportion of immature T cells occurring with age.

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