[Basic elements of antibiotic prophylaxis: the rationale]

In brief, the following study shows the necessity of chemoantibioticprophylaxis. This is to be carried out in operations where the risk of contamination is probable. The antibiotic is to be administered before the operation. Active drugs are used to confront foreseen pathogenics and ensure sufficient M.I.C. for the duration of the operation itself. Moreover, the results obtained from a polycentric research are underlined. The results show post-operative infections, with particular importance being placed on the antibiotics to be used as far as isolated germs are concerned.