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Benign "metastatic" cellular blue nevus

A Bortolani1, D Barisoni, G Scomazzoni

  • 1Department of Plastic.

Annals of Plastic Surgery
|October 1, 1994
PubMed
Summary
This summary is machine-generated.

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This case report details a patient with a foot lesion and inguinal mass, initially suspected as melanoma. Diagnosis confirmed cellular blue nevus, a benign condition, with successful surgical treatment and long-term survival.

Area of Science:

  • Dermatology
  • Pathology
  • Surgical Oncology

Background:

  • Metastatic melanoma is a serious concern for pigmented skin lesions with associated lymphadenopathy.
  • Accurate differential diagnosis is crucial for appropriate patient management and prognosis.

Observation:

  • A patient presented with a dorsal foot pigmented lesion and a homolateral inguinal mass, clinically suggestive of metastatic melanoma.
  • Histological examination revealed spindle cells without atypia in the foot lesion and pigmented cells in the inguinal lymph nodes.
  • The inguinal mass contained blue nevus cells and melanophages, distinct from typical melanoma.

Findings:

  • Differential diagnosis between cellular blue nevus and nodular melanoma was essential.
  • Immunohistochemistry was positive for S-100 protein and negative for HMB-45, supporting cellular blue nevus.

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  • The patient showed no recurrence 5 years post-wide, conservative surgical excision.

    • Implications:

    • Cellular blue nevus can mimic melanoma, necessitating careful histopathological and immunohistochemical evaluation.
    • Wide, conservative surgery is the recommended treatment for cellular blue nevus.
    • Benign clinical course observed in this case highlights the importance of accurate diagnosis.