Use of in vitro human metabolism studies in drug development. An industrial perspective

Reimagining the Framework Supporting the Static Analysis of Transporter Drug Interaction Risk; Integrated Use of Biomarkers to Generate Pan-Transporter Inhibition Signatures.

Clinical pharmacology and therapeutics·2022

First-principles calculations and Raman scattering evidence for local symmetry lowering in rhombohedral ilmenite: temperature- and pressure-dependent studies.

Journal of physics. Condensed matter : an Institute of Physics journal·2018

Impacts of estrus expression and intensity during a timed-AI protocol on variables associated with fertility and pregnancy success in Bos indicus-influenced beef cows.

Journal of animal science·2018

Impact of a timed-release FSH treatment from 2 to 6 months of age in bulls I: Endocrine and testicular development of beef bulls.

Theriogenology·2017

Impact of a timed-release FSH treatment from 2 to 6 months of age in bulls II: Endocrinology, puberty attainment, and mature sperm production in Holstein bulls.

Theriogenology·2017

Endogenous Probes for Drug Transporters: Balancing Vision With Reality.

Clinical pharmacology and therapeutics·2017

Src inhibition attenuates neuroinflammation via promoting p62 UFMylation-dependent microglial mitophagy.

Biochemical pharmacology·2026

Sephin1 directly targets PHB2 to activate PINK1-PRKN-dependent mitophagy and alleviate α-synuclein neurotoxicity in Parkinson's disease models.

Biochemical pharmacology·2026

Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling.

Biochemical pharmacology·2026

Damage-associated molecular patterns in skeletal muscle: a double-edged sword - from sterile inflammation initiation to precision targeted therapeutic strategies.

Biochemical pharmacology·2026

Melatonin attenuates hyperglycemia-induced platelet dysfunction by preserving redox balance and mitochondrial function.

Biochemical pharmacology·2026

Kuwanon E sensitizes hepatocellular carcinoma cells to disulfidptosis via MTOR-mediated autophagy blockade.

Biochemical pharmacology·2026

Establishment of a Low-Level Laser Irradiation Protocol for In Vitro Development of Bovine Embryos.

Veterinary sciences·2026

Research Advances on the Functions of Transcriptional Regulators in Filamentous Fungi.

Microorganisms·2026

Occurrence and Characterization of the Pathogenic Potential of Bacillus cereus in Vending Machines from Southern Italy.

Foods (Basel, Switzerland)·2026

Lactic Acid Bacteria-Fermented Natural Products: Mechanisms and Evidence for Ageing- and Stem-Cell-Related Outcomes.

Foods (Basel, Switzerland)·2026

Biodiversity of NSLAB in Traditional Serbian Cheeses and Stepwise Functional Characterization of Selected Autochthonous Lactobacillus Strains Through Technological, Probiotic and Intestinal Epithelial Interaction Assessment.

Foods (Basel, Switzerland)·2026

Genomic Characterization of Bacterial Isolates from Aerobic Fermentation of Oolong Tea Dregs: Antimicrobial Resistance, Virulence, and Lignocellulose-Degrading Potential.

Foods (Basel, Switzerland)·2026

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Use of in vitro human metabolism studies in drug development. An industrial perspective

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Reimagining the Framework Supporting the Static Analysis of Transporter Drug Interaction Risk; Integrated Use of Biomarkers to Generate Pan-Transporter Inhibition Signatures.

First-principles calculations and Raman scattering evidence for local symmetry lowering in rhombohedral ilmenite: temperature- and pressure-dependent studies.

Impacts of estrus expression and intensity during a timed-AI protocol on variables associated with fertility and pregnancy success in Bos indicus-influenced beef cows.

Impact of a timed-release FSH treatment from 2 to 6 months of age in bulls I: Endocrine and testicular development of beef bulls.

Impact of a timed-release FSH treatment from 2 to 6 months of age in bulls II: Endocrinology, puberty attainment, and mature sperm production in Holstein bulls.

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Src inhibition attenuates neuroinflammation via promoting p62 UFMylation-dependent microglial mitophagy.

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Trans-zeatin suppresses osteoclastogenesis and prevents estrogen deficiency-induced bone loss by modulating Nrf2-mediated redox homeostasis and AKT signaling.

Damage-associated molecular patterns in skeletal muscle: a double-edged sword - from sterile inflammation initiation to precision targeted therapeutic strategies.

Melatonin attenuates hyperglycemia-induced platelet dysfunction by preserving redox balance and mitochondrial function.

Kuwanon E sensitizes hepatocellular carcinoma cells to disulfidptosis via MTOR-mediated autophagy blockade.

Establishment of a Low-Level Laser Irradiation Protocol for In Vitro Development of Bovine Embryos.

Research Advances on the Functions of Transcriptional Regulators in Filamentous Fungi.

Occurrence and Characterization of the Pathogenic Potential of Bacillus cereus in Vending Machines from Southern Italy.

Lactic Acid Bacteria-Fermented Natural Products: Mechanisms and Evidence for Ageing- and Stem-Cell-Related Outcomes.

Biodiversity of NSLAB in Traditional Serbian Cheeses and Stepwise Functional Characterization of Selected Autochthonous Lactobacillus Strains Through Technological, Probiotic and Intestinal Epithelial Interaction Assessment.

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Use of in vitro human metabolism studies in drug development. An industrial perspective

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