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Molecular cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme
D S Tewari1, Y Qian, R D Thornton
1Department of Biochemistry/Molecular Biology, Philadelphia College of Osteopathic Medicine, PA 19131.
Biochimica Et Biophysica Acta
|December 14, 1994
Abstract:
We report the cloning of a cDNA encoding the human homolog of ornithine decarboxylase antizyme from a human gingival fibroblast cDNA library. The human antizyme is 84% identical to the rat sequence and shows almost no homology to the E. coli antizyme. Northern analysis studies show that this gene is expressed in both human gingival and synovial fibroblasts.