Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Total cholesterol and suicidality in depression

P F Sullivan1, P R Joyce, C M Bulik

  • 1University Department of Psychological Medicine, Christchurch School of Medicine, Christchurch, New Zealand.

Biological Psychiatry
|October 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

NDVI changes in the Arctic: Functional significance in the moist acidic tundra of Northern Alaska.

PloS one·2023
Same author

Dysregulation of Synaptic and Developmental Transcriptomic/Proteomic Profiles upon Depletion of MUNC18-1.

eNeuro·2022
Same author

Technological readiness and implementation of genomic-driven precision medicine for complex diseases.

Journal of internal medicine·2021
Same author

Risk of eating disorders in international adoptees: a cohort study using Swedish national population registers.

Epidemiology and psychiatric sciences·2020
Same author

Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions.

Science advances·2020
Same author

Unraveling the genetic architecture of major depressive disorder: merits and pitfalls of the approaches used in genome-wide association studies.

Psychological medicine·2019
Same journal

Functional connectivity of orbitofrontal cortex predicts cocaine relapse: Protective and risk circuits, individual differences, and neuromodulation implications.

Biological psychiatry·2026
Same journal

Takeda G protein-coupled receptor 5 orchestrates anxiolysis by enhancing anterior paraventricular thalamic nucleus glutamatergic neuronal activity to engage distinct downstream circuits.

Biological psychiatry·2026
Same journal

Neuroimaging of Heterogeneity in Neuropsychiatric Disorders: Toward Disease Progression Modeling.

Biological psychiatry·2026
Same journal

Impact of Transcranial Direct Current Stimulation-Induced Electric Fields on Slowing Cognitive Decline in Older Adults With Mild Cognitive Impairment or Remitted Major Depressive Disorder: An Analysis of the PACt-MD Randomized Clinical Trial.

Biological psychiatry·2026
Same journal

Remembering Jon-Kar Zubieta, M.D., Ph.D.

Biological psychiatry·2026
Same journal

Kappa opioid receptor availability in borderline personality disorder: An in-vivo investigation with [<sup>11</sup>C]EKAP PET imaging.

Biological psychiatry·2026
See all related articles

Low cholesterol levels may be linked to increased suicidality in depressed individuals. Further research is warranted to explore this association between total cholesterol and suicidal behaviors in patients with depression.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Biochemistry

Background:

  • Controversy exists regarding the association between low total cholesterol and increased suicide mortality.
  • Suicide mortality is an indirect indicator of suicidal ideation and behavior.

Purpose of the Study:

  • To investigate the relationship between total cholesterol levels and suicidality.
  • To examine this association within a sample of individuals diagnosed with major depressive disorder.

Main Methods:

  • Ninety participants with major depressive episodes were assessed.
  • Suicidality was categorized into three levels: no suicidal thoughts, suicidal ideation/plan, and suicide attempt.
  • Univariate and multivariate analyses were employed to assess the association.

Related Experiment Videos

Main Results:

  • A significant univariate association was observed between lower cholesterol levels and increased degrees of suicidality.
  • This association approached statistical significance in the multivariate analysis (p = 0.068).

Conclusions:

  • The findings suggest a potential link between lower total cholesterol and heightened suicidality in depressed patients.
  • While not conclusive, the data support further investigation into this association.