[Techniques of security of plasma transfusion]

Viral inactivation of fresh frozen plasma (FFP) is the main condition of a safe administration in its few remaining indications. Different techniques have been developed such as "quarantine", solvent-detergent plasma treatment, pasteurization or, more recently, photosensitizing agents adjunction. None of these techniques is entirely satisfactory and further clinical studies are needed. Meanwhile, FFP use must be restricted to some well known congenital ou acquired pathologies where it cannot be substituted.