Cutaneous T-cell lymphoma diagnosed by fine-needle aspiration: a case report with clinical, cytological, and
1Department of Pathology, Maulana Azad Medical College, New Delhi, India.
Abstract:
A case study of cutaneous T-cell lymphoma in a 40-yr-old Indian male is presented. Prominent clinical features consisted of large skin tumours, lymphadenopathy, and a rapidly progressive course of development. Aspiration smears from tumours, lymph nodes, and bone marrow showed pleomorphic Sezary cells and lymphoid blasts. The neoplastic cells stained positively with anti-HLA DR, CD1, and CD2 antibodies and showed lack of T-cell subset antigens CD4 and CD8. Numerous proliferating cells were identified with 56% of bone marrow cells and 57% of cells in the dermis staining positively with Ki-67 and PC10 antibodies, respectively. This case is reported in view of its uncommon features.
